Summary: This Week in The Journal
F Cellular/Molecular
Watching Synapses Mature
Edward S. Ruthazer, Jianli Li, and
Hollis T. Cline
(see pages 3594­3603)
Martin P. Meyer and Stephen J. Smith
(see pages 3604­3614)
Neural activity influences ongoing re-
modeling of axonal arbors, a phenome-
non that is particularly evident in the de-
velopment of the retinotectal system of
fish and tadpoles. Two papers this week
give us a multicolor view of these systems
at work. Ruthazer et al. watched the
growth of retinal ganglion cells (RGCs) in
albino tadpoles, whereas Meyer and
Smith used zebrafish. Both authors ex-
pressed cytosolic dsRED (discosoma red
fluorescent protein) and GFP (green fluo-

Source: Andersen, Richard - Division of Biology, California Institute of Technology

Collections: Biology and Medicine