Home

About

Advanced Search

Browse by Discipline

Scientific Societies

E-print Alerts

Add E-prints

E-print Network
FAQHELPSITE MAPCONTACT US


  Advanced Search  

 
The Journal of Neuroscience, September 1995, 15(g): 6250-6259 Tissue-Specific Expression of a Drosophila Calcium-Activated
 

Summary: The Journal of Neuroscience, September 1995, 15(g): 6250-6259
Tissue-Specific Expression of a Drosophila Calcium-Activated
Potassium Channel
Marie N. Becker," Robert Brenner, and Nigel S. Atkinson
Department of Zoology, The University of Texas at Austin, Austin, Texas 78712-1064
The Drosophila slowpoke (s/o) gene encodes a subunit of
a CAK channel homologous to the vertebrate BK channel.
We have examined s/o expression throughout develop-
ment. It is expressed in muscle cells, neurons of the CNS
and PNS, mushroom bodies, a limited number of cells in
embryonic and larval midgut and in epithelial-derived tra-
cheal cells. The promoter has been cloned and shown to
direct expression in the same pattern as the endogenous
gene in both neural and epithelial-derived cells. During pu-
pariation and embryogenesis, s/o is expressed in muscles
many hours prior to the appearance of functional channels.
[Key words: C&+-activated K+ channel, Drosophila, slow-
poke, development, gene expression, reporter gene, anti-
body1
A cell's electrical properties are determined by the complement

  

Source: Atkinson, Nigel - Section of Neurobiology, Division of Biological Sciences, University of Texas at Austin

 

Collections: Biology and Medicine