Summary: 1
Synaptic cleft
20-40 nm
vesicles
Presynaptic
density
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(A) A presynaptic terminal forming glutamatergic synapses with two dendritic spines. Synaptic vesicles
containing glutamate cluster at the site of synaptic contact. (B) Tracing of (A), identifying major synaptic
structures. The dendritic shaft contains microtubules along which material is transported from the cell body.
Spines contain an actin cytoskeleton that confers movement (73) and permits transport of material toward the
PSD at the tip of the spine. Scale bar in (A), 400 nm.
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SNARE complex and Ca2+ sensor
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Clathrin-mediated endocytosis
Invagination Constriction
UncoatingFission
Clathrin triskelion AP-2 (binds to clathrin an PIP2)
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Source: Alford, Simon - Department of Biological Sciences, University of Illinois at Chicago

Collections: Biology and Medicine