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780 nature neuroscience volume 2 no 9 september 1999 news and views
 

Summary: 780 nature neuroscience volume 2 no 9 september 1999
news and views
brain nuclei, all begin long before most
neurons and glia are generated (see ref. 6
for review). We now have an enormous list
of genes that are expressed in patterns sug-
gesting involvement in these processes.
These data, plus the morphological devel-
opment of the embryonic forebrain, sug-
gest that much of the patterning occurs
between roughly E9 and E13. This new
method may therefore be enormously valu-
able for manipulating the brain at a critical
time during its development.
Although this is primarily a techniques
paper, it also provides some interesting
insights into the phenomenon of `retroviral
silencing'7. If undifferentiated embryonic
carcinoma (EC) cells are infected with retro-
virus, the provirus integrates into the host

  

Source: Anagnostaras, Stephan - Neurosciences Program & Department of Psychology, University of California at San Diego

 

Collections: Biology and Medicine