Advanced Search

Browse by Discipline

Scientific Societies

E-print Alerts

Add E-prints

E-print Network

  Advanced Search  

Behavioral/Systems/Cognitive Resolution of Sensory Ambiguities for Gaze Stabilization

Summary: Behavioral/Systems/Cognitive
Resolution of Sensory Ambiguities for Gaze Stabilization
Requires a Second Neural Integrator
Andrea M. Green and Dora E. Angelaki
Department of Anatomy and Neurobiology, Washington University School of Medicine, St. Louis, Missouri 63110
ocular reflexes (VORs) to gaze stabilization. It is traditionally believed that semicircular canal signals drive compensatory responses to
rotational head disturbances (rotational VOR), whereas otolith signals compensate for translational movements [translational VOR
(TVOR)]. However, a sensory ambiguity exists because otolith afferents are activated similarly during head translations and reorienta-
tions relative to gravity (i.e., tilts). Extra-otolith cues are, therefore, necessary to ensure that dynamic head tilts do not elicit a TVOR. To
investigate how extra-otolith signals contribute, we characterized the temporal and viewing distance-dependent properties of a TVOR
addition to otolith signals, angular head position signals derived by integrating sensory canal information drive the TVOR. A physiolog-
ical basis for these results is proposed in a model with two distinct integration steps. Upstream of the well known oculomotor velocity-
to-position neural integrator, the model incorporates a separate integration element that could represent the "velocity storage integra-
tor," whose functional role in the oculomotor system has so far remained controversial. We propose that a key functional purpose of the
from ambiguous otolith afferent signals in the natural and functionally relevant bandwidth of head movements.
Key words: eye movement; vestibular; oculomotor; sensorimotor; model; otolith; VOR; velocity storage


Source: Angelaki, Dora - Department of Anatomy and Neurobiology, Washington University in St. Louis


Collections: Biology and Medicine