 
Summary: Phys 597A, CMPS 497E
Graphs and Networks in Systems Biology
Lecturer: Réka Albert
ralbert@phys.psu.edu
122 Davey Laboratory
Networks, networks everywhere
ˇ Network infrastructure, social networking
ˇ Network  a tool for understanding complex systems
ˇ Many nonidentical elements connected by diverse interactions
ˇ E.g. interaction networks within cells: protein interactions,
chemical reactions, gene regulation
ˇ Graph measures provide information on interaction graphs
ˇ Network models explain and predict properties of graph classes
ˇ Network topology influences network robustness and the
dynamics of flows
ˇ E.g. dynamics of molecular interaction networks determines the
behavior of cells.
ˇ Understand emergent properties synchronization, phase
transitions, homeostasis
Definition of graphs (networks)Definition of graphs (networks)
