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JOURNAL OF VIROLOGY, Feb. 2009, p. 18811891 Vol. 83, No. 4 0022-538X/09/$08.00 0 doi:10.1128/JVI.01805-08
 

Summary: JOURNAL OF VIROLOGY, Feb. 2009, p. 18811891 Vol. 83, No. 4
0022-538X/09/$08.00 0 doi:10.1128/JVI.01805-08
Copyright 2009, American Society for Microbiology. All Rights Reserved.
Novel Influenza Virus NS1 Antagonists Block Replication and Restore
Innate Immune Function
Dipanwita Basu,1
Marcin P. Walkiewicz,1
Matthew Frieman,2
Ralph S. Baric,2
David T. Auble,3
and Daniel A. Engel1
*
Department of Microbiology, University of Virginia School of Medicine, Charlottesville, Virginia 229081
; Department of Epidemiology,
School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 275992
; and Department of
Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia 229083
Received 27 August 2008/Accepted 24 November 2008
The innate immune system guards against virus infection through a variety of mechanisms including
mobilization of the host interferon system, which attacks viral products mainly at a posttranscriptional level.

  

Source: Auble, David - Department of Biochemistry and Molecular Genetics, University of Virginia

 

Collections: Biology and Medicine