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Resistance to Bacillus thuringiensis Toxin in Caenorhabditis elegans from Loss of Fucose*
 

Summary: Resistance to Bacillus thuringiensis Toxin in Caenorhabditis
elegans from Loss of Fucose*
Received for publication,July 12, 2006, and in revised form, November 9, 2006 Published, JBC Papers in Press,November 29, 2006, DOI 10.1074/jbc.M606621200
Brad D. Barrows
, Stuart M. Haslam§
, Larry J. Bischof
, Howard R. Morris§¶
, Anne Dell§1
, and Raffi V. Aroian2
From the
Section of Cell and Developmental Biology, University of California, San Diego, La Jolla, California 92093-0349,
§
Division of Molecular Biosciences, Faculty of Natural Sciences, Imperial College London, London SW7 2AZ, United Kingdom,
and ¶
M-SCAN Research and Training Center, Silwood Park, Ascot SL5 7PZ, United Kingdom
A mutation in the Caenorhabditis elegans bre-1 gene was iso-
lated in a screen for Bacillus thuringiensis toxin-resistant (bre)
mutants to the Cry5B crystal toxin made by B. thuringiensis.
bre-1 mutant animals are different from the four other cloned
bre mutants in that their level of resistance is noticeably lo-

  

Source: Aroian, Raffi V. - Division of Biological Sciences, University of California at San Diego

 

Collections: Biology and Medicine