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Dispersion control in nano-channel systems by localized z-potential variations
 

Summary: Dispersion control in nano-channel systems
by localized z-potential variations
R. Qiao, N.R. Aluru*
Department of General Engineering, 3265 Beckman Institute for Advanced Science and Technology,
University of Illinois at Urbana-Champaign, MC-251, 405 North Mathews Avenue,
Urbana, IL 61801, USA
Abstract
Turns and bends, such as an L-turn or a U-turn, in micro and nano-fluidic channels can induce significant dispersion leading to a low
efficiency electrophoretic separation process. It has been shown that turn-induced dispersion can be lowered by optimizing the geometry of the
turns. In this paper, we propose a new approach for controlling turn-induced dispersion in nano-fluidic channels. The approach is based on the
idea of locally controlling the z-potential at turns and bends. An optimization algorithm was developed to search for the optimal configuration
of the z-potential near turns. Results for an L-turn and a U-turn show that the dispersion can be lowered significantly by a localized z-potential
variation near the turn.
# 2003 Elsevier Science B.V. All rights reserved.
Keywords: Dispersion control; Nano-fluidic channels; z-Potential; Optimization
1. Introduction
There has been a growing interest in developing minia-
turized fluidic devices for transport, separation and detec-
tion of bio-samples. In many of these devices, capillary
electrophoresis is used for sample separation, and electro-

  

Source: Aluru, Narayana R. - Department of Mechanical and Industrial Engineering, University of Illinois at Urbana-Champaign

 

Collections: Engineering; Materials Science