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Kinesin: world's tiniest biped Charles L Asbury
 

Summary: Kinesin: world's tiniest biped
Charles L Asbury
Kinesin, an essential motor protein that moves intracellular
cargo along microtubules, walks like a person. When we
walk, our feet exchange roles with each step, one moving and
one remaining stationary. The moving foot travels twice as far
as our torso during a single step, and our body alternates
between two configurations (left vs. right leg leading). Recent
work shows that kinesin shares all three of these hallmarks
of bipedal walking. The challenge now is to determine how
the gait of this lilliputian biped is coordinated.
Addresses
Department of Physiology and Biophysics, University of Washington
School of Medicine, Seattle, Washington 98195-7290, USA
Corresponding author: Asbury, Charles L (casbury@u.washington.edu)
Current Opinion in Cell Biology 2005, 17:8997
This review comes from a themed issue on
Cell structure and dynamics
Edited by Anthony A Hyman and Jonathon Howard
Available online 15th December 2004

  

Source: Asbury, Chip - Department of Physiology and Biophysics, University of Washington at Seattle

 

Collections: Biology and Medicine