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INFECTION AND IMMUNITY, Sept. 2009, p. 39693977 Vol. 77, No. 9 0019-9567/09/$08.00 0 doi:10.1128/IAI.01362-08
 

Summary: INFECTION AND IMMUNITY, Sept. 2009, p. 39693977 Vol. 77, No. 9
0019-9567/09/$08.00 0 doi:10.1128/IAI.01362-08
Copyright 2009, American Society for Microbiology. All Rights Reserved.
Role of the Type III Secretion System in a Hypervirulent Lineage of
Bordetella bronchiseptica
Anne M. Buboltz,1,2
Tracy L. Nicholson,3
Laura S. Weyrich,1,2
and Eric T. Harvill1
*
Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, 115 Henning Building, University Park,
Pennsylvania 168021
; Graduate Program in Biochemistry, Microbiology, and Molecular Biology, The Pennsylvania State University,
108 Althouse Building, University Park, Pennsylvania 168022
; and Respiratory Diseases of Livestock Research Unit,
National Animal Disease Center, Agricultural Research Service, USDA, Ames, Iowa3
Received 6 November 2008/Returned for modification 16 December 2008/Accepted 2 July 2009
Despite the fact that closely related bacteria can cause different levels of disease, the genetic changes that
cause some isolates to be more pathogenic than others are generally not well understood. We use a combination
of approaches to determine which factors contribute to the increased virulence of a Bordetella bronchiseptica

  

Source: Andrews, Anne M. - Huck Institutes of the Life Sciences, Pennsylvania State University

 

Collections: Biology and Medicine