Summary: 1767© 2011 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim wileyonlinelibrary.comsmall 2011, 7, No. 13, 17671773
In nature, materials that exhibit significant magnetism and
efficient luminescence rarely exist.
Such materials are
highly desirable in a number of potential biological applica-
tions including drug and gene delivery, bio-sensing, and bio-
imaging with magnetic resonance imaging (MRI) contrast.
Recently, some reports have focused on the synthesis and
applications of bifunctional nanomaterials such as hybrid
and coreshell nanocomposites.
All of these materials are
either composites or hybrid structures combining lumines-
cent and magnetic materials individually. In these materials,
organic dyes or metal complexes were immobilized on a
silica layer, which leads to critical problems of leaching and
Alternatively, semiconductor quantum
dots such as CdS, CdSe, and CdTe, have been demonstrated
to be highly effective for cellular and animal imaging. How-