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R E V I E W : E V O L U T I O N Bayesian Inference of Phylogeny and

Summary: R E V I E W : E V O L U T I O N
Bayesian Inference of Phylogeny and
Its Impact on Evolutionary Biology
John P. Huelsenbeck,1
* Fredrik Ronquist,2
Rasmus Nielsen,3
Jonathan P. Bollback1
As a discipline, phylogenetics is becoming transformed by a flood of molecular data.
These data allow broad questions to be asked about the history of life, but also
present difficult statistical and computational problems. Bayesian inference of phy-
logeny brings a new perspective to a number of outstanding issues in evolutionary
biology, including the analysis of large phylogenetic trees and complex evolutionary
models and the detection of the footprint of natural selection in DNA sequences.
he idea that species are related through a
history of common descent is an old one,
predating Darwin. Yet the idea provides
an organizing principle in biology that has pro-
found importance for a number of fundamental
questions. These questions range from the ba-


Source: Anisimova, Maria - Institute of Scientific Computing, Eidgenössische Technische Hochschule Zürich (ETHZ)


Collections: Biology and Medicine