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Mechanism for top-down control of working memory capacity

Summary: Mechanism for top-down control of working
memory capacity
Fredrik Edina,b,c,1
, Torkel Klingberga,c
, Pa¨r Johanssona,c
, Fiona McNaba,c
, Jesper Tegne´ra,d
, and Albert Comptea,e,1
aKarolinska Institutet, 171 76 Stockholm, Sweden; bKungliga Tekniska Ho¨ gskolan, 100 44 Stockholm, Sweden; cStockholm Brain Institute, 171 76 Stockholm,
Sweden; dLinko¨ pings Tekniska Ho¨ gskola, 581 53 Linko¨ ping, Sweden; and eInstitut d'Investigacions Biome`diques August Pi i Sunyer, 08036 Barcelona, Spain
Communicated by Ranulfo Romo, Universidad Nacional Auto´ noma de Me´xico, Mexico, D.F., Mexico, February 27, 2009 (received for review
October 20, 2008)
Working memory capacity, the maximum number of items that we
can transiently store in working memory, is a good predictor of our
general cognitive abilities. Neural activity in both dorsolateral
prefrontal cortex and posterior parietal cortex has been associated
with memory retention during visuospatial working memory tasks.
The parietal cortex is thought to store the memories. However, the
role of the dorsolateral prefrontal cortex, a top-down control area,
during pure information retention is debated, and the mechanisms


Source: Andrzejak, Ralph Gregor - Departament de Tecnologia, Universitat Pompeu Fabra


Collections: Computer Technologies and Information Sciences