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Summary: LETTERS
Epithelial-cell-intrinsic IKK-b expression regulates
intestinal immune homeostasis
Colby Zaph1
, Amy E. Troy1
, Betsy C. Taylor1
, Lisa D. Berman-Booty1
, Katherine J. Guild1
, Yurong Du1
, Evan A. Yost1
,
Achim D. Gruber3
, Michael J. May2
, Florian R. Greten4
{, Lars Eckmann5
, Michael Karin4
& David Artis1
Intestinal epithelial cells (IECs) provide a primary physical barrier
against commensal and pathogenic microorganisms in the gastro-
intestinal (GI) tract, but the influence of IECs on the development
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