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Summary: H
unger focuses the mind. And hunger
is what Mario Capecchi remembers
most from his early childhood,
which was spent on the streets of war-torn
Italy. Today a contender for a Nobel prize,
the geneticist attributes the single-minded-
ness and fearlessness that has underpinned
his scientific success to this formative strug-
gle for survival.
Capecchi, who works at the University of
Utah in Salt Lake City, is fęted for his contri-
bution to methods for selectively knocking
out genes in mice -- widely used to investi-
gate gene function and to create animal
models to study human disease.Yet while he
was conducting the experiments that made
his name, none of Capecchi's peers knew of
hisharrowingchildhoodexperiences.
Whenhespokeoutforthefirsttime,while
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