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A Bioinspired Ugi/Michael/aza-Michael Cascade Reaction in Aqueous Media: Natural Product-Like Molecular Diversity
 

Summary: SI 1

A Bioinspired Ugi/Michael/aza-Michael Cascade Reaction in Aqueous Media:
Natural Product-Like Molecular Diversity
Soumava Santra & Peter R. Andreana*
Department of Chemistry,
Wayne State University,
5101 Cass Ave,
Detroit, MI 48202
Email: pra@chem.wayne.edu
Supporting Information
Materials and Methods: All Reagents were purchased from Aldrich unless otherwise
mentioned. 4-Hydroxybezaldehyde, 4-hydroxy-3-methoxybenzaldehyde, 4-hydroxy-3,5-
dimethoxybenzaldehyde, 4-hydroxy-3-bromobenzaldehyde, 4-hydroxy-3-methoxy-5-
nitrobenzaldehyde, and 4-hydroxy-1-napthaldehyde were purchased from Alfa Aesar. 4-
hydroxy-2-methoxybenzaldehyde was purchased from ASDI Product List, and 4-
hydroxy-2,6-dimethoxybenzaldehyde was purchased from Frinton Labs. 4-hydroxy-2-
nitrobenzaldehyde was purchased from TCI America. 4-hydroxy-2-fluorobenzaldehyde
was purchased from Matrix Scientific. tert-Butyl isocyanide was purchased from TCI
America. Adamantyl-1-isocyanide was synthesized according to literature precedent

  

Source: Andreana, Peter R. - Department of Chemistry, Wayne State University

 

Collections: Chemistry