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Multiagent-Based Simulation in Biology: A Critical Analysis
 

Summary: Multiagent-Based Simulation in Biology:
A Critical Analysis
Francesco Amigoni1
and Viola Schiaffonati2
1
Dipartimento di Elettronica e Informazione, Politecnico di Milano
amigoni@elet.polimi.it
2
Dipartimento di Elettronica e Informazione, Politecnico di Milano
schiaffo@elet.polimi.it
Summary. In this paper we critically analyze the use of multiagent systems for
performing simulations of biological processes. From the one hand, the possibility
of associating different elements of a biological process to independent computing
entities, called agents, makes multiagent systems a powerful and flexible tool for
simulation. From the other hand, the weak validation of the results obtained makes
multiagent-based simulations hard to trust. We discuss these issues by referring to
a specific example, the simulation of a signal transduction pathway.
1 Introduction
Computer simulations [RS02] are an important tool to investigate the properties of
biological systems that are difficult to study in more traditional ways, for example

  

Source: Amigoni, Francesco - Dipartimento di Elettronica e Informazione, Politecnico di Milano

 

Collections: Computer Technologies and Information Sciences