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ORIGINAL ARTICLE Alia T. Tuqan Kristen M. Kelly Guillermo Aguilar

Alia T. Tuqan Kristen M. Kelly Guillermo Aguilar
Julio C. Ramirez-San-Juan Chung-Ho Sun
David Cassarino Damian Derienzo
Ronald J. Barr J. Stuart. Nelson
Evaluation of single versus multiple cryogen spray cooling spurts
on in vitro model human skin
Received: 12 January 2005 / Accepted: 23 May 2005 / Published online: 30 August 2005
Springer-Verlag London Limited 2005
Abstract Many commercially available dermatologic
lasers utilize cryogen spray cooling for epidermal pro-
tection. A previous tissue culture study demonstrated
that single cryogen spurts (SCS) of 80 ms or less were
unlikely to cause cryo-injury in light-skinned individu-
als. More recently, multiple cryogen spurts (MCS) have
been incorporated into commercial devices, but the ef-
fects of MCS have not been evaluated. The aim was to
study an in vitro tissue culture model and the epidermal
and dermal effects of SCS vs patterns of shorter MCS
with the same preset total cryogen delivery time (Dtc)


Source: Aguilar, Guillermo - Department of Mechanical Engineering, University of California at Riverside


Collections: Engineering