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Negative Autoregulation Speeds the Response Times of Transcription Networks
 

Summary: Negative Autoregulation Speeds the Response Times
of Transcription Networks
Nitzan Rosenfeld1
, Michael B. Elowitz2
and Uri Alon1
*
1
Department of Molecular Cell
Biology, Department of Physics
of Complex Systems
Weizmann Institute of Science
Rehovot 76100, Israel
2
Rockefeller University, 1230
York Avenue, New York, NY
10021, USA
Cells regulate gene expression using networks of transcription inter-
actions; it is of interest to discover the principles that govern the dynamical
behavior of such networks. An important characteristic of these systems is
the rise-time: the delay from the initiation of production until half maximal

  

Source: Alon, Uri - Departments of Molecular Cell Biology & Physics of Complex Systems, Weizmann Institute of Science
Elowitz, Michael - Division of Biology, California Institute of Technology

 

Collections: Biology and Medicine