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Detection of fluorescent-labeled probes at sub-picomolar concentrations by magnetic
 

Summary: Detection of fluorescent-labeled probes at sub-
picomolar concentrations by magnetic
modulation
Amos Danielli,1,*
Ady Arie,1
Noga Porat,2
and Marcelo Ehrlich3
1
Department of Physical Electronics, Faculty of Engineering, Tel-Aviv University, Tel-Aviv 69978, Israel
2
Department of Biological Science, University of Illinois at Chicago, Chicago IL 60607, USA
3
Department of Cell Research and Immunology, Tel-Aviv University, Tel-Aviv 69978, Israel
*
Corresponding author: amosd@post.tau.ac.il
Abstract: A sensitive and rapid method for detecting fluorescent dyes at
low concentrations in homogenous solution is experimentally demonstrated.
Fluorescent-labeled DNA probes are detected by attaching magnetic beads
and applying alternating magnetic field gradient. This condenses the
fluorescent probes into a small detection volume and eliminates the

  

Source: Arie, Ady - Department of Electrical Engineering-Physical Electronics, Tel Aviv University

 

Collections: Engineering