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In Vivo Measurement of Pulsewave Velocity in Small Vessels Using Intravascular MR
 

Summary: In Vivo Measurement of Pulsewave Velocity in Small
Vessels Using Intravascular MR
Bradley D. Bolster, Jr.,1
Jean-Michel Serfaty,2
and Ergin Atalar2*
A one-dimensional intravascular MR (IVMR) technique for the
measurement of pulsewave velocity in a single cardiac cycle is
presented. The technique was used to measure pulsewave ve-
locity in vivo in the intact rabbit model, where its sensitivity to
different hemodynamic states was demonstrated using a phar-
macological intervention with phenylephrine and nitroprusside.
IVMR measurements of pulsewave velocity were found to in-
crease with mean arterial pressure, as expected. Further,
IVMR-based pulsewave velocity estimates were in agreement
with those measured by pressure catheters and direct disten-
sibility measurement. Because of their rapidity and highly local-
ized nature, these measurements of vessel elasticity may
complement the high-resolution vascular imaging informa-
tion gained in an IVMR examination. This could allow assess-
ment of atherosclerotic plaques and facilitate immediate

  

Source: Atalar, Ergin - Department of Electrical and Electronics Engineering, Bilkent University

 

Collections: Engineering; Biology and Medicine