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Regeneration in the metazoans: why does it happen?
 

Summary: Regeneration in the metazoans:
why does it happen?
Alejandro Sa nchez Alvarado
Summary
Why does regeneration occur? And why, when it
manifests itself, does it do so in some but not all
metazoan species? Hence, what are the permissive or
inhibitory factors operating behind this phenomenon?
When it comes to regeneration, many questions, such
as these, remain unanswered. In fact, the problem of
animal regeneration has withstood the probing of
scientific inquiry for over 250 years and still awaits a
satisfactory mechanistic explanation. In this essay, I will
review the distribution and the modes of regeneration
that are found in the different metazoan phyla. Also, I
will re-examine ideas on its evolutionary origins, and
discuss its possible relationship to both asexual
reproduction and embryogenesis. This endeavor has
two objectives. First, to bring forward an interpretation
of regeneration which integrates evolutionary and

  

Source: Alvarado, Alejandro Sánchez - Department of Neurobiology and Anatomy, University of Utah

 

Collections: Biology and Medicine