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Summary: INFECTION AND IMMUNITY,
0019-9567/99/$04.00 0
Dec. 1999, p. 63296334 Vol. 67, No. 12
Copyright © 1999, American Society for Microbiology. All Rights Reserved.
Comparative Analysis of Glycosylated and Nonglycosylated Filarial
Homologues of the 20-Kilodalton Retinol Binding
Protein from Onchocerca volvulus (Ov20)
NIROSHINI NIRMALAN,1
N. J. V. CORDEIRO,2
SABINE L. KLA¨GER,1
JANETTE E. BRADLEY,1
AND JUDITH E. ALLEN2
*
Department of Biological Sciences, University of Salford, Salford M5 4WT,1
and ICAPB Ashworth
Laboratories, University of Edinburgh, Edinburgh EH9 3JT,2
United Kingdom
Received 30 June 1999/Returned for modification 16 August 1999/Accepted 9 September 1999
Ov20 is a structurally novel 20-kDa retinol binding protein secreted by Onchocerca volvulus. Immunological
and biological investigation of this protein has been hampered by the inability to maintain O. volvulus in a
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