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RED CELLS, IRON, AND ERYTHROPOIESIS Brief report
 

Summary: RED CELLS, IRON, AND ERYTHROPOIESIS
Brief report
Agenome-wide association analysis of serum iron concentrations
Toshiko Tanaka,1,2 Cindy N. Roy,3 Wenliang Yao,3 Amy Matteini,3 Richard D. Semba,4 Dan Arking,3 Jeremy D. Walston,3
Linda P. Fried,5 Andrew Singleton,6 Jack Guralnik,7 Gonc¸alo R. Abecasis,8 Stefania Bandinelli,9 Dan L. Longo,2 and
Luigi Ferrucci2
1MedStar Research Institute, Baltimore, MD; 2Clinical Research Branch, National Institute on Aging, Baltimore, MD; 3Division of Geriatric Medicine and
Gerontology, Johns Hopkins University School of Medicine and 4Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD;
5Columbia University Joseph L. Mailman School of Public Health, Columbia University, New York, NY; 6Laboratory of Neurogenetics and 7Laboratory of
Epidemiology, Demography and Biometry, National Institute on Aging, Bethesda, MD; 8Center for Statistical Genetics, Department of Biostatistics, University of
Michigan, Ann Arbor; and 9Geriatric Unit, Azienda Sanitaria Firenze, Florence, Italy
To investigate genetic variants that affect
iron concentrations in persons not af-
fected by overt genetic disorders of iron
metabolism, a genome-wide association
study was conducted in the InCHIANTI
Study (N 1206) and the Baltimore Longi-
tudinal Study of Aging (N 713). The top
2 single-nucleotide polymorphisms were
examined for replication in the Women's

  

Source: Abecasis, Goncalo - Department of Biostatistics, University of Michigan

 

Collections: Biology and Medicine; Mathematics