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YEAST VOL. 13: 583589 (1997) Sequence Analysis of a 332 kb Segment from the Left

Summary: YEAST VOL. 13: 583589 (1997)
Sequence Analysis of a 332 kb Segment from the Left
Arm of Yeast Chromosome XV Reveals Eight Known
Genes and Ten New Open Reading Frames Including
Homologues of ABC Transporters, Inositol
Phosphatases and Human Expressed Sequence Tags
Foundation for Research and Technology-HELLAS, Institute of Molecular Biology and Biotechnology, Crete, Greece
Department of Biology, University of Crete, Crete, Greece
Received 15 August 1996; accepted 25 October 1996
The complete nucleotide sequence of a 33 221 bp segment, contained in cosmid pEOA1044, derived from the left arm
of chromosome XV of Saccharomyces cerevisiae, appears in public databases between coordinates 177013 and
210234 (http://speedy.mips.biochem.mpg.de/). Computer analysis of that sequence revealed the presence of the
previously known genes IRA2, DEC1, NUF2, HST1, RTG1, RIB2 and HAL2, one previously partially sequenced
open reading frame (ORF) of unknown function (SCORFAC) and ten newly identified ORFs. One of the new ORFs
is similar to the Drosophila melanogaster white gene and other transmembrane ABC transporters, another one has
similarities to inositol phosphatases and others are similar to ORFs of unknown function from various organisms,
including human Expressed Sequence Tags (ESTs). Potential transmembrane regions, ATP/GTP-binding and WD
motifs have also been identified. The existence of yeast ESTs for two of the newly identified ORFs indicates that they
are transcribed. 1997 by John Wiley & Sons, Ltd.


Source: Alexandraki, Despina - Institute of Molecular Biology and Biotechnology, Foundation of Research and Technology, Hellas


Collections: Biology and Medicine; Biotechnology