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Heritability of reproductive fitness traits in a human population

Summary: Heritability of reproductive fitness traits
in a human population
Gülüm Kosovaa,b
, Mark Abneyb
, and Carole Obera,b,c,1
Committee on Genetics, Genomics, and Systems Biology, and Departments of b
Human Genetics and c
Obstetrics and Gynecology, University of Chicago,
Chicago, IL 60637
Edited by Diddahally R. Govindaraju, Boston University School of Medicine, and accepted by the Editorial Board September 10, 2009 (received for review
July 6, 2009)
The genetic basis of fitness traits has been studied widely in
animals, yet the contribution of genetic variation to these traits in
humans is controversial. In particular, it is difficult to disentangle
genetic versus environmental effects on fertility, because of with-
in-family correlations of sociocultural, economic, and other non-
genetic factors that influence family sizes. In this study, we inves-
tigated the genetic architecture of reproductive fitness traits in a
fertile human population whose communal lifestyle assures uni-


Source: Abney, Mark - Department of Human Genetics, University of Chicago


Collections: Computer Technologies and Information Sciences; Biology and Medicine