Summary: Published: March 16, 2011
r 2011 American Chemical Society 5659 dx.doi.org/10.1021/jp112174s |J. Phys. Chem. B 2011, 115, 5659­5664
ARTICLE
pubs.acs.org/JPCB
UV Resonance Raman Finds Peptide BondÀArg Side Chain Electronic
Interactions
Bhavya Sharma and Sanford A. Asher*
Department of Chemistry, University of Pittsburgh, 219 Parkman Avenue, Pittsburgh, Pennsylvania 15260, United States
' INTRODUCTION
There is little understanding of the electronic transitions of
peptides and proteins.1À10
It is generally assumed that peptide
and protein electronic transitions result from the summation of
the electronic transitions of the constituent chromophores. The
peptide bond f * transitions have been characterized to a
limited extent, as have been the transitions of the different
isolated side chain chromophores.1À13
However, there has been
little attention paid to the potential coupling of the peptide bond
transitions to the side chain electronic transitions or to coupling

Source: Asher, Sanford A. - Department of Chemistry, University of Pittsburgh

Collections: Materials Science; Chemistry