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SHORT COMMUNICATION The effect of pathogens on selection against deleterious mutations
 

Summary: SHORT COMMUNICATION
The effect of pathogens on selection against deleterious mutations
in Drosophila melanogaster
JADENE A.YOUNG, CHRISTOPHER P. YOURTH & ANEIL F. AGRAWAL
Department of Ecology & Evolutionary Biology, University of Toronto, Toronto, ON, Canada
Introduction
It remains somewhat unclear why most organisms
regularly shuffle their genomes through sex and recom-
bination (Otto & Lenormand, 2002; Agrawal, 2006a).
Much effort has been put into finding an explanation
that is broadly applicable to diverse taxa. Because all
natural populations suffer from both parasites and
deleterious mutations, a large number of theoretical sex
models have focused on either parasites (Hamilton et al.,
1990; Peters & Lively, 1999; Agrawal, 2006b) or muta-
tions (Kondrashov, 1982; Agrawal & Chasnov, 2001;
Keightley & Otto, 2006).
However, there has been comparatively little effort
expended on investigating the joint action of parasites
and deleterious mutations in selecting for sex. Indeed,

  

Source: Agrawal, Aneil F. - Department of Ecology and Evolutionary Biology, University of Toronto

 

Collections: Environmental Sciences and Ecology