Summary: SELF-ORGANIZATION AND NEURONAL AVALANCHES IN NETWORKS
OF DISSOCIATED CORTICAL NEURONS
V. PASQUALE,a
P. MASSOBRIO,b
L. L. BOLOGNA,a
M. CHIAPPALONEa
AND S. MARTINOIAb
*
a
Neuroscience and Brain Technology Department, Italian Institute of
Technology, Via Morego 30, 16163 Genova, Italy
b
Neuroengineering and Bio-nano Technology Group, Department of
Biophysical and Electronic Engineering, University of Genova, Via
all'Opera Pia 11A, 16145 Genova, Italy
Abstract--Dissociated cortical neurons from rat embryos
cultured onto micro-electrode arrays exhibit characteristic
patterns of electrophysiological activity, ranging from iso-
lated spikes in the first days of development to highly syn-
chronized bursts after 3­4 weeks in vitro. In this work we

Source: Arleo, Angelo - Laboratory of Neurobiology of Adaptive Processes, Université Pierre-et-Marie-Curie, Paris 6

Collections: Biology and Medicine