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Summary: The VLDB Journal (2005) 14(3): 330353
DOI 10.1007/s00778-005-0158-4
REGULAR PAPER
Snehal Thakkar · José Luis Ambite ·
Craig A. Knoblock
Composing, optimizing, and executing plans
for bioinformatics web services
Received: 7 July 2005 / Accepted: 7 June 2005 / Published online: 26 September 2005
c Springer-Verlag 2005
Abstract The emergence of a large number of bioinformat-
ics datasets on the Internet has resulted in the need for flex-
ible and efficient approaches to integrate information from
multiple bioinformatics data sources and services. In this pa-
per, we present our approach to automatically generate com-
position plans for web services, optimize the composition
plans, and execute these plans efficiently. While data integra-
tion techniques have been applied to the bioinformatics do-
main, the focus has been on answering specific user queries.
In contrast, we focus on automatically generating parame-
terized integration plans that can be hosted as web services
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