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Biochemistry Insect Biochemistry and Molecular Biology 35 (2005) 105115
 

Summary: Insect
Biochemistry
and
Molecular
Biology
Insect Biochemistry and Molecular Biology 35 (2005) 105115
An antimicrobial peptide with trypanocidal activity characterized
from Glossina morsitans morsitans
Youjia Hua,b
, Serap Aksoya,
a
Department of Epidemiology and Public Health, Section of Vector Biology, Yale University, School of Medicine, 60 College St., 606 LEPH,
New Haven, CT 06510, USA
b
Department of Biology, Shanghai Institute of Pharmaceutical Industry, 1320 Beijing Xi Lu, Shanghai 200040, China
Received 29 July 2004; accepted 5 October 2004
Abstract
Tsetse flies (Diptera:Glossinidae) are vectors of African trypanosomes, the protozoan agents of devastating diseases in humans
and animals. Prior studies in trypanosome infected Glossina morsitans morsitans have shown induced expression and synthesis of
several antimicrobial peptides in fat body tissue. Here, we have expressed one of these peptides, Attacin (GmAttA1) in Drosophila

  

Source: Aksoy, Serap - School of Public Health, Yale University

 

Collections: Biology and Medicine