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Original Research Development of an Intravascular Heating Source
 

Summary: Original Research
Development of an Intravascular Heating Source
Using an MR Imaging Guidewire
Bensheng Qiu, PhD, Christopher J. Yeung, BS, Xiangying Du, MD, Ergin Atalar, PhD,
and Xiaoming Yang, MD, PhD*
Purpose: To develop a novel endovascular heating source
using a magnetic resonance (MR) imaging guidewire
(MRIG) to deliver controlled microwave energy into the tar-
get vessel for thermal enhancement of vascular gene trans-
fection.
Materials and Methods: A 0.032-inch MRIG was con-
nected to a 2.45-GHz microwave generator. We 1) calcu-
lated the microwave power loss along the MRIG, 2) simu-
lated the power distribution around the MRIG, 3) measured
the temperature increase vs. input power with the MRIG,
and 4) evaluated the thermal effect on the balloon-com-
pressed/microwave-heated aorta of six living rabbits. In
addition, during balloon inflation, we also simultaneously
generated high-resolution MR images of the aortic wall.
Results: The power loss was calculated to be 3.9 dB along

  

Source: Atalar, Ergin - Department of Electrical and Electronics Engineering, Bilkent University

 

Collections: Engineering; Biology and Medicine