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Homozygous DNA ligase IV R278H mutation in mice leads to leaky SCID and represents a model for
 

Summary: Homozygous DNA ligase IV R278H mutation in mice
leads to leaky SCID and represents a model for
human LIG4 syndrome
Francesca Ruccia,1
, Luigi D. Notarangeloa,2
, Alex Fazelib
, Laura Patrizia
, Thomas Hickernellb
, Tiziana Paganinic
,
Kristen M. Coakleyb
, Cynthia Detred
, Marton Keszeid
, Jolan E. Waltera
, Lauren Feldmane
, Hwei-Ling Chengb
,
Pietro Luigi Polianif
, Jing H. Wangb
, Barbara B. Balterd

  

Source: Alt,, Frederick - Immune Disease Institute, Harvard University

 

Collections: Biology and Medicine