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THEJOURNALOFCELLBIOLOGY JCB: ARTICLE
 

Summary: THEJOURNALOFCELLBIOLOGY
JCB: ARTICLE
The Rockefeller University Press $30.00
J. Cell Biol. Vol. 183 No. 3 485498
www.jcb.org/cgi/doi/10.1083/jcb.200806009 JCB 485
Correspondence to Vadim Y. Arshavsky: vadim.arshavsky@duke.edu
Abbreviation used in this paper: mGluR1, metabotropic glutamate receptor 1.
The online version of this article contains supplemental material.
Introduction
Normal vision is dependent on the function of rod and cone
photoreceptors, which are sensory neurons proven to be among
the most productive model systems for studying signal trans-
duction and sensory physiology. The key feature that makes
them so amenable is their highly compartmentalized organiza-
tion. Photoreceptors consist of four major compartments: a
photosensitive outer segment containing highly packed disc
membranes and the proteins required to initiate a response to
light, an inner segment where proteins and lipids are synthe-
sized and energy is produced, a nuclear region, and a synaptic
terminal that sends information to the second order neurons in

  

Source: Arshavsky, Vadim Y. - Department of Pharmacology, Duke University

 

Collections: Biology and Medicine