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Summary: SHORT REPORT
HLA-class II haplotype associations with ovarian cancer
Kirsten Kubler1
, Peter F. Arndt2
, Eva Wardelmann3
, Dieter Krebs1
, Walther Kuhn1
and Katrin van der Ven1*
1
Department of Obstetrics and Gynecology, University of Bonn, Sigmund Freud Strasse 25, 53127 Bonn, Germany
2
Department for Computational Molecular Biology, Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany
3
Department of Pathology, University of Bonn, Sigmund Freud Strasse 25, 53127 Bonn, Germany
The development of cancer is a multistep process that is charac-
terized by the accumulation of genetic alterations in cells and
changed cellular interactions with the surrounding healthy tissues.
The human immune system is believed to be intrinsically involved
in this process. The correlation of certain human leukocyte anti-
gen (HLA)-class I and II haplotypes with tumorigenesis is docu-
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