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Analysis with Mathematical Models Provides Insights into Infectious Diseases

Summary: Analysis with Mathematical Models
Provides Insights into Infectious Diseases
Modeling can help address questions about pathogen turnover, immune
system responses, and pathogen spread within populations
Olivier Restif, Juilee Thakar, and Eric T. Harvill
uch of microbiological research
on infectious agents is increas-
ingly specialized and reduction-
ist, viewing the host as a virtually
static environment and thus
sharply narrowing the context of the disease
under study. We advocate an alternative quan-
titative approach that enables investigators to
go beyond their reliance on conventional and
somewhat simplified qualitative terms for de-
scribing experimental outcomes--typically,
"gene x is required to control infection y."
While those conventional approaches give
rise to detailed knowledge of components in-


Source: Andrews, Anne M. - Huck Institutes of the Life Sciences, Pennsylvania State University


Collections: Biology and Medicine