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MAGNETIC RESONANCE IN CHEMISTRY Magn. Reson. Chem. 2005; 43: 688696
 

Summary: MAGNETIC RESONANCE IN CHEMISTRY
Magn. Reson. Chem. 2005; 43: 688696
Published online in Wiley InterScience (www.interscience.wiley.com). DOI: 10.1002/mrc.1616
Review
Nuclear magnetic resonance coupled microseparations
A. G. Webb
Department of Electrical and Computer Engineering and Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-
Champaign, Urbana, Illinois 61801, USA
Received 2 December 2004; Revised 1 April 2005; Accepted 12 April 2005
The increased separation efficiency afforded by reducing the size of the separation column has resulted
in `microseparations' becoming an important component in many chemical and biochemical applications.
The coupling of microseparations with NMR detection is an area of increasing interest owing to the
high structural information of NMR. In order to couple efficiently with the separation, the NMR detector
must be reduced in size to correspond to that of the separation peak. This paper summarizes some of the
approaches used in coupling NMR detection with pressure-driven and electrophoretic microseparations,
the design of small NMR detectors and applications of this technology. Copyright 2005 John Wiley &
Sons, Ltd.
KEYWORDS: NMR; limits of detection; microcoils; microseparations; capillary liquid chromatography; capillary
electrophoresis; capillary isotachophoresis; hyphenation
INTRODUCTION

  

Source: Andrews, Anne M. - Huck Institutes of the Life Sciences, Pennsylvania State University

 

Collections: Biology and Medicine