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Evaluation of Gallium-68 Tris(2-Mercaptobenzyl)Amine: A Complex with Brain and Myocardial Uptake
 

Summary: Evaluation of Gallium-68 Tris(2-Mercaptobenzyl)Amine:
A Complex with Brain and Myocardial Uptake
Cathy S. Cutler,1
M. Cecilia Giron,1
David E. Reichert,1
Abraham Z. Snyder,1
Pilar Herrero,1
Carolyn J. Anderson,1
Duncan A. Quarless,2
Stephen A. Koch2
and
Michael J. Welch1
1
THE EDWARD MALLINCKRODT INSTITUTE OF RADIOLOGY, WASHINGTON UNIVERSITY SCHOOL OF MEDICINE, ST. LOUIS,
MISSOURI, USA; AND 2
DEPARTMENT OF CHEMISTRY, STATE UNIVERSITY OF NEW YORK AT STONY BROOK,
STONY BROOK, NEW YORK, USA
ABSTRACT. Previous research into development of a gallium-radiolabeled agent that crosses the blood­
brain barrier has met with limited success. In this study, we focused our attention on a Ga(III) complex of
a 4-coordinate amine trithiolate tripod ligand, tris(2-mercaptobenzyl) amine (S3N). The Ga(III) S3N

  

Source: Anderson, Carolyn J. - Department of Molecular Biology and Pharmacology, Washington University in St. Louis

 

Collections: Biology and Medicine