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In vitro maturation of human oocytes and cumulus cells using a co-culture three-dimensional collagen gel system
 

Summary: In vitro maturation of human oocytes and cumulus cells
using a co-culture three-dimensional collagen gel system
Catherine M.H.Combelles1,5
, Rafael A.Fissore2
, David F.Albertini3,4
and Catherine Racowsky1
1
Brigham and Women's Hospital, Harvard Medical School, Department of Obstetrics and Gynecology, Boston, MA 02115,
2
University of Massachusetts, Department of Veterinary and Animal Sciences, Amherst, MA 01003 and 3
Tufts University
School of Medicine, Department of Anatomy and Cellular Biology, Boston, MA 02111, USA
4
Current address: The University of Kansas Medical Center, Department of Molecular and Integrative Physiology, Kansas City,
KS 66160, USA
5
To whom correspondence should be addressed at: Biology Department, McCardell Bicentennial Hall 350, Middlebury College,
Middlebury, VT 05753, USA. E-mail: ccombell@middlebury.edu
BACKGROUND: Deficiencies remain in the ability of in vitro-matured human oocytes to acquire full developmental
competence and give rise to a healthy pregnancy. A clear deficiency of current systems utilizing human oocytes has

  

Source: Albertini, David - Center for Reproductive Sciences, University of Kansas

 

Collections: Biology and Medicine