Home

About

Advanced Search

Browse by Discipline

Scientific Societies

E-print Alerts

Add E-prints

E-print Network
FAQHELPSITE MAPCONTACT US


  Advanced Search  

 
N,N-Ethylenedi-L-cysteine (EC) and Its Metal Complexes: Synthesis, Characterization, Crystal Structures, and Equilibrium Constants
 

Summary: N,N-Ethylenedi-L-cysteine (EC) and Its Metal Complexes: Synthesis, Characterization,
Crystal Structures, and Equilibrium Constants
Yuejin Li, Arthur E. Martell,*, Robert D. Hancock, Joseph H. Reibenspies,
Carolyn J. Anderson, and Michael J. Welch
Department of Chemistry, Texas A&M University, College Station, Texas 77843-3225,
The Edward Mallinckrodt Institute of Radiology, Washington University School of Medicine,
St. Louis, Missouri 63110, and Department of Chemistry, University of the Witwatersrand,
Johannesburg, South Africa
ReceiVed NoVember 17, 1994X
N,N-ethylenedi-L-cysteine (EC) and its indium(III) and gallium(III) complexes have been synthesized and
characterized. The crystal structures of the ligand and the complexes have been determined by single-crystal
X-ray diffraction. EC,2HBr,2H2O (C8H22Br2N2O6S2) crystallizes in the orthorhombic space group P21212 with
a ) 12.776(3) , b ) 13.735(2) , c ) 5.1340 (10) , Z ) 2, and V ) 900.9(3) 3. The complexes
Na[M(III)EC],2H2O (C8H16MN2O6S2Na) are isostructural for M ) In and Ga, crystallizing in the tetragonal
space group P42212 with the following lattice constants for In, (Ga): a ) 10.068(2) , (9.802(2) ), b ) 10.068-
(2) , (9.802(2) ), c ) 14.932(2) , (15.170(11) ), Z ) 4 (4), and V ) 1513.6(5) 3, (1457.5(11) 3). In
both metal complexes, the metal atoms (In and Ga) are coordinated by six donor atoms (N2S2O2) in distorted
octahedral coordination geometries in which two sulfur atoms and two nitrogen atoms occupy the equatorial
positions, and the axial positions are occupied by two oxygen atoms of two carboxylate groups. The structures
of the complexes previously predicted by molecular mechanics are compared with the crystal structures of the

  

Source: Anderson, Carolyn J. - Department of Molecular Biology and Pharmacology, Washington University in St. Louis

 

Collections: Biology and Medicine