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A Psycho -Physiological model of longevity Paper presented at visit to Athens Sept 2007

Summary: 1
A Psycho - Physiological model of longevity
Paper presented at visit to Athens Sept 2007
Bo Hagberg
Dept of Psychology
Lund University, Sweden
For a long time now wear and tear has been around in gerontology as one way of
explaining aging differences and differences in longevity, i.e. why different persons age
with different speed and why some people live longer than other even up to 100 years of
age or more. Today I want to present some ideas and data that support this notion. So I
will talk along the following themes :
Pic 1 The synopsis
Pic 2 Wear and tear
Wear and tear was first formulated as a theory of aging by Weismann in 1882 as the
Abnutzungstheorie, states that the replacement of damaged or worn out parts, is not perfect
enough or does not occur at a rate sufficient to compensate for the deleterious effects of
time. In modern times the same idea was reflected by Kirkwood and others (1979) in the
"disposable soma theory" that predicts the accumulation of unrepaired damage through
life, senile degeneration ultimately death.
The mechanisms that I propose to be responsible for these processes is the lifelong


Source: Arnold, Jonathan - Nanoscale Science and Engineering Center & Department of Genetics, University of Georgia


Collections: Biotechnology