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Summary: 2
Fractional Anisotropy of White Matter Tract Contrasted between Complex
Regional Pain Syndrome and Normal Controls
P.Y.Geha1, A. Narang1, M.N. Baliki1, N.R. Harden2, W.Bauer3, D.R. Chialvo1 , A.V. Apkarian1
1.Department of Physiology, Northwestern University 2. Physical Medicine & Rehabilitation, Rehabilitation Institute of Chicago, Chicago, IL
Northwestern University, Chicago, IL 60611 3. Neuroscience & Rehabilitation Medicine, Medical College Ohio, Toledo, OH
SFN 2006
Atlanta
159.15
Chronic pain is associated with cortical
functional, neurochemical and
morphological changes (Apkarian et al.,
2001, Grachev et al., 2002, Apkarian et al.,
2004). Furthermore, complex regional pain
syndrome (CRPS) patients exhibit a specific
deficit on an emotional decision making
task, suggestive of damage to the
medial/orbito-frontal cortex (Apkarian et al.,
2004). Here we hypothesize the
occurrence of white matter changes,
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