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Real-Time Imaging of Two-Dimensional Cardiac Strain Using a Harmonic Phase Magnetic Resonance Imaging
 

Summary: Real-Time Imaging of Two-Dimensional Cardiac Strain
Using a Harmonic Phase Magnetic Resonance Imaging
(HARP-MRI) Pulse Sequence
Smita Sampath,1
J. Andrew Derbyshire,2
Ergin Atalar,3
Nael F. Osman,3
and Jerry L. Prince1,3*
The harmonic phase (HARP) method provides automatic and
rapid analysis of tagged magnetic resonance (MR) images for
quantification and visualization of myocardial strain. In this
article, the development and implementation of a pulse se-
quence that acquires HARP images in real time are described.
In this pulse sequence, a CINE sequence of images with 1-1
spatial modulation of magnetization (SPAMM) tags are acquired
during each cardiac cycle, alternating between vertical and
horizontal tags in successive heartbeats. An incrementing train
of imaging RF flip angles is used to compensate for the decay
of the harmonic peaks due to both T1 relaxation and the applied
imaging pulses. The magnitude images displaying coarse anat-

  

Source: Atalar, Ergin - Department of Electrical and Electronics Engineering, Bilkent University
Prince, Jerry L. - Department of Electrical and Computer Engineering, Johns Hopkins University

 

Collections: Biology and Medicine; Computer Technologies and Information Sciences; Engineering