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New models of collaboration in genome-wide association studies: the Genetic

New models of collaboration in genome-
wide association studies: the Genetic
Association Information Network
The GAIN Collaborative Research Group
The Genetic Association Information Network (GAIN) is a public-private partnership established
to investigate the genetic basis of common diseases through a series of collaborative genome-
wide association studies. GAIN has used new approaches for project selection, data deposition and
distribution, collaborative analysis, publication and protection from premature intellectual property
claims. These demonstrate a new commitment to shared scientific knowledge that should facilitate rapid
advances in understanding the genetics of complex diseases.
Genome-wide association (GWA) studies of
large numbers of individuals genotyped for
hundreds of thousands of common genetic
variants have now convincingly been shown
to be effective in identifying genes related to
health and disease110. The growing under-
standing of genome variation provided by
the International HapMap Consortium11
and continued major advances in genotyping


Source: Abecasis, Goncalo - Department of Biostatistics, University of Michigan


Collections: Biology and Medicine; Mathematics