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5th International Symposium on Multiphase Flow, Heat Mass Transfer and Energy Conversion Xi'an, China, 3-6 July 2005
 

Summary: 5th International Symposium on Multiphase Flow, Heat Mass Transfer and Energy Conversion
Xi'an, China, 3-6 July 2005
Numerical Analysis of Tissue Freezing in Cutaneous Cryosurgery
Using Liquid Nitrogen Spray
Feng SUN1
, G.-X. WANG1,
*, Kristen M. KELLY2
, Guillermo AGUILAR3
1. Mechanical Engineering Department, The University of Akron, Akron, OH, 44325-3901, USA
2. Beckman Laser Institute, University of California, Irvine, CA 92612-1475, USA
3. Department of Mechanical Engineering, University of California Riverside, CA 92521, USA
Abstract Information on thermal history of skin tissue and iceball formation is critical for successful cutaneous
cryosurgery. This paper presents a numerical analysis of tissue freezing during skin cancer treatment with liquid
nitrogen (LN2). A simplified mathematical model is constructed by including the bio-physical processes of the freezing
tissues and quantifying LN2 spray cooling with a convective heat transfer coefficient. Propagations of iceball fronts as
well as lethal temperature isotherms are illustrated and quantitatively examined under various spray cooling conditions.
The injury mechanisms of skin cells at different locations are also investigated based on corresponding thermal history
and cooling rates during cryosurgery. These quantitative evaluations will be useful for pretreatment planning and
optimization of LN2 spray cryosurgical protocols.
1. Introduction

  

Source: Aguilar, Guillermo - Department of Mechanical Engineering, University of California at Riverside

 

Collections: Engineering