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RESEARCH PAPER Use of a porous membrane for gas bubble removal in microfluidic
 

Summary: RESEARCH PAPER
Use of a porous membrane for gas bubble removal in microfluidic
channels: physical mechanisms and design criteria
Jie Xu Regis Vaillant Daniel Attinger
Received: 1 January 2010 / Accepted: 7 March 2010
Springer-Verlag 2010
Abstract We demonstrate and explain a simple and
efficient way to remove gas bubbles from liquid-filled
microchannels, by integrating a hydrophobic porous
membrane on top of the microchannel. A prototype chip is
manufactured in hard, transparent polymer with the ability
to completely filter gas plugs out of a segmented flow at
rates up to 7.4 ll/s/mm2
of membrane area. The device
involves a bubble generation section and a gas removal
section. In the bubble generation section, a T-junction is
used to generate a train of gas plugs into a water stream.
These gas plugs are then transported toward the gas
removal section, where they slide along a hydrophobic
membrane until complete removal. The system has been

  

Source: Attinger, Daniel - Department of Mechanical Engineering, Columbia University

 

Collections: Engineering