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INFECTION AND IMMUNITY, 0019-9567/00/$04.00 0
 

Summary: INFECTION AND IMMUNITY,
0019-9567/00/$04.00 0
May 2000, p. 25132517 Vol. 68, No. 5
Copyright 2000, American Society for Microbiology. All Rights Reserved.
Interleukin-5 Is Essential for Vaccine-Mediated Immunity but
Not Innate Resistance to a Filarial Parasite
LAETITIA LE GOFF,1
P'NG LOKE,1
H. FAHIMEDA ALI,1
DAVID W. TAYLOR,2
AND JUDITH E. ALLEN1
*
Institute of Cell, Animal and Population Biology, University of Edinburgh, Edinburgh EH9 3JT,1
and Centre for Tropical Veterinary Medicine, University of Edinburgh,
Roslin EH25 9RG,2
United Kingdom
Received 8 November 1999/Returned for modification 11 January 2000/Accepted 26 January 2000
The study of protective immune mechanisms effective against filarial nematodes has been hampered by the
inability of these important human pathogens to infect laboratory mice. Recently, Litomosoides sigmodontis, a
natural parasite of rats, has been developed as a valuable model for the study of filarial infection. BALB/c mice

  

Source: Allen, Judith - School of Biological Sciences, University of Edinburgh

 

Collections: Biology and Medicine