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Communication Reduced data acquisition time in multi-dimensional
 

Summary: Communication
Reduced data acquisition time in multi-dimensional
NMR spectroscopy using multiple-coil probes
Han Wanga,b
, Luisa Ciobanub
, Andrew Webba,b,*
a
Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
b
Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA
Received 21 September 2004; revised 18 November 2004
Available online 7 January 2005
Abstract
A new hardware-based approach is presented to reduce data acquisition times in multi-dimensional NMR spectroscopy using a
multiple-coil probe. Using a four-coil setup, two-dimensional COSY and TOCSY spectra were acquired in one-quarter the time of
conventional spectra by simultaneous acquisition of different effective t1 evolution times for each coil. Data processing consists of
simple phase-shifting and intensity normalization of the individual data sets, and results in spectra almost identical to those acquired
in a conventional manner. This method can potentially be integrated with other new data acquisition and processing schemes for
further increases in data acquisition speed.
2004 Elsevier Inc. All rights reserved.

  

Source: Andrews, Anne M. - Huck Institutes of the Life Sciences, Pennsylvania State University

 

Collections: Biology and Medicine