Summary: Bactericidal efficacy of electrospun pure and Fe-doped titania nanofibers
and Ryan Hershey
Department of Chemical Engineering, The University of Toledo, Toledo, Ohio 435606-3390
The Ohio State University, Columbus, Ohio 43210-1173
Departments of Bioengineering and Orthopedic Surgery, The University of Toledo,
Toledo, Ohio 435606-3390
(Received 24 February 2010; accepted 20 April 2010)
This paper reports the development of nonwoven nanofibers of pure and iron-doped
titanium dioxide (TiO2) and evaluation of their antimicrobial attributes for using them as
disinfectant gauze for wound healing upon brief activation by ultraviolet/infrared (UV/IR)
illumination. It was found that the fibers exhibited superior bactericidal affinity when
exposed briefly (312 s) to either multiphoton laser or infrared radiations. On the other
hand, exposure to a UV beam for up to 20 min was not effective in mitigating the bacterial
colonization of the Escherichia coli.
Tissue engineering has received extensive attention in
recent years as an emerging and rapidly growing field.